An all too common contributor to irreproducible research is the widespread use of misidentified or contaminated cell lines. It is estimated that 15% to 36% of cell lines in use right now are not what you think they are.
GBSI facilitates the work of the Alliance and through #authenticate, our periodic e-newsletter.
GBSI shares the progress and innovations of Alliance members and the broader research community towards achieving our goals.
Achieve correctly identified cell lines that are contaminant-free.
Required documentation of cell authentication for publication in journals.
Improved training and technologies for researchers on best practices for cell authentication.
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Visibility & Action
It is our primary objective to make key stakeholders aware of the powerful role cell line authentication plays in research reproducibility.
Tools & Technologies
We aim to provide a greater investment in new technologies to develop novel tools for cell authentication.
The campaign has engaged researchers, funders, journals, societies, industry leaders, and others while encouraging the scientific community to share their findings.
Rigor Through Policy
In response to heightened awareness, NIH and other funders have incorporated stated policies that emphasize the validation of key biological reagents, including cell lines, in their grant application and review processes. Leading journals have done the same in their checklists of author submission and peer review.
Training & Proficiency
The campaign provides standards and best practices surrounding cell line authentication that researchers can follow.